MBS/Pharmacy Joint Seminar - "Unraveling the Evolutionary Principles of Cancer"
Mar
3
2025
Mar
3
2025
Description
The Molecular Biosciences Department and the College of Pharmacy welcome Dr. Matthew Jones for a joint seminar.
Dr. Jones completed his PhD in Bioinformatics at UC San Francisco and UC Berkeley and is currently a Postdoctoral Scholar at Stanford University in Howard Chang's lab.
Dr. Jones seminar, “Unraveling the Evolutionary Principles of Cancer” will be held on Monday, March 3 at 12:00 PM in BME 3.204 and via zoom.
Click here to learn more about Dr. Jones' research.
Abstract
My current research focuses on building more predictive models of tumor evolution, with a focus on how circular, oncogenic extrachromosomal DNA (ecDNA) reshape traditional rules of inheritance to accelerate tumor evolution and overcome targeted therapies. A key outcome of my research thus far is contributing to the discovery that ecDNA amplifications are often co-inherited during mitosis, leading to non-coding oncogenic amplifications and new therapeutic opportunities. Previously, I developed single-cell evolving lineage tracing technologies and computational tools. In this, I developed Cassiopeia, a software suite for reconstructing single-cell phylogenies from continuous CRISPR/Cas9 barcoding data. We used these tools to study how aggressive cancers evolve from a single transformed cell and eventually metastasize throughout a body.
Location
BME 3.204
This virtual event requires software to participate. Get help with Zoom or Microsoft Teams.
Share
Other Events in This Series
Mar
24
2027
MPR Seminar - Title TBD
MBS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Andrew Weems
Mar
25
2027
ILS Seminar - Sahu, Woodman, Cabrera
ILS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Aparna Sahu, Joseph Woodman, and Mica Cabrera
Mar
25
2027
ILS Seminar - Moore, Urbanic, Chapman
ILS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): John Moore, Megan Urbanic, and Victoria Chapman
Mar
31
2027
MBS Seminar - Title TBD
MBS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Peijun Zhang
Apr
1
2027
ILS Seminar - Huo, Lawson, Chayan Ali
ILS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Da Huo, Dani Lawson, and Md Chayan Ali
Apr
7
2027
MBS Seminar - Title TBD
MBS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Alexander Sobolevsky
Apr
14
2027
TYR Seminar - Title TBD
MBS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Sanchita Bhadra
Apr
15
2027
ILS Seminar - Sharma
ILS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Mansi Sharma
Apr
21
2027
MPR Seminar - Title TBD
MBS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Zunlong Ke
Apr
22
2027
ILS Seminar - Grad Students TBD
ILS Spring 2027 Seminar Series
12:00 pm – 1:30 pm • In Person