MBS/Pharmacy Joint Seminar - "Unraveling the Evolutionary Principles of Cancer"
Mar
3
2025
Mar
3
2025
Description
The Molecular Biosciences Department and the College of Pharmacy welcome Dr. Matthew Jones for a joint seminar.
Dr. Jones completed his PhD in Bioinformatics at UC San Francisco and UC Berkeley and is currently a Postdoctoral Scholar at Stanford University in Howard Chang's lab.
Dr. Jones seminar, “Unraveling the Evolutionary Principles of Cancer” will be held on Monday, March 3 at 12:00 PM in BME 3.204 and via zoom.
Click here to learn more about Dr. Jones' research.
Abstract
My current research focuses on building more predictive models of tumor evolution, with a focus on how circular, oncogenic extrachromosomal DNA (ecDNA) reshape traditional rules of inheritance to accelerate tumor evolution and overcome targeted therapies. A key outcome of my research thus far is contributing to the discovery that ecDNA amplifications are often co-inherited during mitosis, leading to non-coding oncogenic amplifications and new therapeutic opportunities. Previously, I developed single-cell evolving lineage tracing technologies and computational tools. In this, I developed Cassiopeia, a software suite for reconstructing single-cell phylogenies from continuous CRISPR/Cas9 barcoding data. We used these tools to study how aggressive cancers evolve from a single transformed cell and eventually metastasize throughout a body.
Location
BME 3.204
This virtual event requires software to participate. Get help with Zoom or Microsoft Teams.
Share
Other Events in This Series
Nov
13
2025
ILS Seminar - "Reversal of Hemoglobin Switching by Cis-Regulatory Interference"
ILS Fall 2025 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Dr. Jennifer Cherone
Nov
19
2025
MBS Seminar - "Molecular Consequence of RNA Modifications and their Impact on the Structure and Dynamics of the Ribosome"
MBS Fall 2025 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Dr. Christine Dunham
Nov
20
2025
ILS Seminar - Doshi, Wang, Lyons
ILS Fall 2025 Seminar Series
12:00 pm – 1:30 pm • In Person
Dec
10
2025
MPR Seminar - "Ubiquitin at the Crossroads: Decoding its Role in Infection, DNA Repair, and Cell Death"
MBS Fall 2025 Seminar Series
12:00 pm – 1:30 pm • In Person
Speaker(s): Dr. Jaime Lopez
Dec
15
2025
MBS Seminar - "Designing Proteins to Modulate Immunity"
12:00 pm – 1:30 pm • Hybrid
Speaker(s): Dr. Rubul Mout
Dec
18
2025
MBS Seminar - "Predicting the Human Protein Interaction and its Implication in Cancer"
12:00 pm – 1:30 pm • Hybrid
Speaker(s): Dr. Jing Zhang
Jan
12
2026
MBS Seminar - "Toward a Mechanistic Understanding of Plant Growth and Stress Signaling"
12:00 pm – 1:30 pm • Hybrid
Speaker(s): Dr. Ping Wang
Jan
15
2026
MBS Seminar - "Linking Cancer Drivers to Programmed Cell Death"
12:00 pm – 1:30 pm • Hybrid
Speaker(s): Dr. Sai Gourisankar
Jan
20
2026
MBS Seminar - "Massively Parallel Discovery of Peptides to Control Cellular Protein Interactions"
12:00 pm – 1:30 pm • Hybrid
Speaker(s): Dr. Andrew Savinov
Jan
22
2026
MBS Seminar - "From Code to Crop: Precise Expression for Enhanced Plant Resistance"
12:00 pm – 1:30 pm • Hybrid
Speaker(s): Dr. Wei Wei
