Xiaolu (Lulu) Lim Ang Cambronne

Lulu Ang Cambronne, Ph.D. is an Associate Professor in the Department of Molecular Biosciences in the College of Natural Sciences. Her research is dedicated to elucidating how compartmentalized metabolism is used by cells and to determine its control mechanisms. Her group develops and uses continuous real-time fluorescent protein biosensors to measure metabolites in live cells. Such sensors are the only approach to date able to metabolically measure in single cells with subcellular resolution from complex and interacting environments. Her work identifies and targets critical metabolic regulators for a deeper understanding of fundamental biology, and for improved metabolic stratification of different cell types.  

Dr. Cambronne received a Hon.B.Sc in Molecular Genetics from the University of Toronto, a Ph.D. with Wade Harper from the Division of Medical Sciences at Harvard University, and received postdoctoral training under Richard Goodman in microRNA target identification as well as NAD+ biology at the Vollum Institute. Dr. Cambronne has organized the international 2024 and 2026 FASEB NAD Metabolism and Signaling Scientific Conferences. Her work has been honored both at the pre-doctoral and post-doctoral levels with individual Kirschstein National Service Research Awards, Albert J Ryan and Samuel Lunenfeld Fellowships, and named the 2013 OHSU New Inventor of the year. She is a 2017 recipient of the NIH Director's New Innovator Award, a 2020 Pew Biomedical Scholar, 2020-2021 Scialog Fellow, 2022 MAVEN Scientist, 2022 William H. Tonn Professorial Fund Fellow, and the 2022-2023 recipient of the College of Natural Sciences Foundation Teaching Excellence Award.

Cambronne’s current research focuses on understanding how metabolites impact cellular signaling cascades and epigenetic regulation. The approach is to track the subcellular availability of specific metabolites using new fluorescent biosensors developed by the lab.