Core Facilities

Advanced laboratories and facilities are essential for the department's pioneering research programs. Explore the college's core facilities below.

Center for Biomedical Research Support

CBRS core facilities support cellular and molecular biology research at The University of Texas at Austin. The facilities offer a full range of services in nucleic acid and protein sequencing, peptide synthesis, mass spectrometry, protein purification and analysis, DNA microarrays, x-ray chrystallography, and transgenic - knockout mice.

The CRBS Core Facilities Include:

Biological Mass Spectrometry 

  • The Proteomics Facility provides services, self-service equipment, and collaborative research for the detection, characterization, and quantification of proteins and other biomolecules

Computational Biology and Bioinformatics

  • The Computational Biology and Bioinformatics core facility provides research opportunities and support for students, postdoctoral fellows, and faculty interested in the use of computational approaches to solving biological problems.


  • The Genomic Sequencing and Analysis Facility (GSAF) provides “next-generation” DNA sequencing (NGS) services and conventional “Sanger” DNA sequencing services.

Molecular Structure 

  • Provides equipment for determination of structures by X-ray dffraction methods.

Microscopy and Flow Cytometry 

  • The Microscopy and Imaging Facility provides extensive microscopy equipment and services for ultra-structural analysis of a variety of sample types. The facility offers assisted use and training on its instrumentation and consultations on microscopy- and spectroscopy-related research.




  • The Mouse Genetic Engineering Facility (MGEF) provides services to generate, maintain, and archive transgenic mice for understanding mammalian gene function and modeling human disease.

Sauer Lab for Structural Biology

The Sauer Structural Biology Laboratory is UT Austin's state-of-the-art cryo-EM facility, housing both an FEI Titan Krios equipped with a Gatan K2 Summit direct electron detector and an FEI Talos also equipped with a Gatan K2 Summit direct electron detector. Both of these instruments are capable of imaging macromolecular machines at atomic or near atomic resolution. The facility also contains all of the accessory equipment required for high-resolution structure determination. The facility is staffed by a Ph.D. level manager, who has many years of experience with electron microscopy.