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Yelland, James

Jamie Yelland

Graduate Research Assistant
Molecular Biosciences

Visualizing the steps of eukaryotic ribosome assembly

Office Location
NMS 1.246

Postal Address
The University of Texas at Austin
2506 SPEEDWAY, Stop A5000
AUSTIN, TX 78712-1191


B.A. Biochemistry, Oberlin College (2013)


Second year graduate student, Biochemistry PhD program, Institute for Cell & Molecular Biology

Advisors: Dr. Arlen Johnson, Dr. David Taylor

Interests: Ribosome biogenesis, structures of nascent ribosomes, ribosome quality control, structural biology

The eukaryotic ribosome is an exceptionally complex macromolecular machine, and cells devote lots of energy to manufacturing lots of ribosomes. Using cryo-electron microscopy and other techniques, I study structures and mechanisms of ribosome assembly in our favorite model eukaryote, S. cerevisiae. I'm investigating how cells build and test the catalytic center of the large ribosomal subunit, which must be properly assembled in order to correctly translate genetic information into proteins. My work will lead to a deeper understanding of how ribosome synthesis, an essential process in all living things, is controlled and monitored at its most critical steps.


Hamilton Seed Grant (Department of Molecular Biosciences, The University of Texas at Austin)


Darmasiswa Scholarship (Ministry of Education & Culture, Republic of Indonesia)