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Yelland, James

Jamie Yelland

Graduate Research Assistant
Molecular Biosciences


Visualizing the steps of eukaryotic ribosome assembly
jyelland@utexas.edu


Office Location
NMS 1.246

Postal Address
2506 SPEEDWAY
AUSTIN, TX 78712

Education

B.A. Biochemistry, Oberlin College (2013)

Advisors: Dr. Arlen Johnson, Dr. David Taylor

Interests: Ribosome biogenesis, structures of nascent ribosomes, ribosome quality control, structural biology

The eukaryotic ribosome is an exceptionally complex macromolecular machine, responsible for protein synthesis in all eukaryotic cells. Using high throughput sequencing, cryo-electron microscopy and other techniques, I study the mechanisms of ribosome assembly in our favorite model eukaryote, S. cerevisiae. In particular, I am elucidating the mechanisms of certain enzymes which cells use to build and test the catalytic center of the large ribosomal subunit. This catalytic center is the site of protein synthesis, and its proper assembly is crucial for cellular function. My work is thus leading to a deeper understanding of how ribosome synthesis, an essential process for life, is monitored and controlled by the cell.
 

Schepers, M. J., Yelland, J. N., Moran, N. A. & Taylor, D. W. Isolation of the Buchnera aphidicola flagellum basal body complexes from the Buchnera membrane. PLoS One 16, e0245710 (2021).

2018

Hamilton Seed Grant (Department of Molecular Biosciences, The University of Texas at Austin)

 

Teaching Assistant

Foundations of Biochemistry (David Hoffman, BCH339F) - Fall 2018

Molecular Machines (Karen Browning, BCH339M) - Fall 2019, Fall 2020