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Stovall, Gwen
No

Gwendolyn M Stovall

Assistant Professor of Practice
College of Natural Sciences


Gwen Stovall leads the FRI Aptamer Stream, where students use biochemistry and molecular biology to develop tools made of RNA and DNA.

gwenstovall@utexas.edu

Phone: 512-232-9358

Office Location
PAI

Postal Address
103 W 24TH ST
AUSTIN, TX 78712

Ph.D., The University of Texas at Austin (2011)

B.S.Chem., The University of Georgia (1999)

B.S. in Biochemistry and Molecular Biology, The University of Georgia (1999)

Research Interests: A part of the University of Texas Freshman Research Initiative, the Aptamer Stream uses oligonucleotide chemistry, in vitro selection methodology, and biochemistry to develop novel therapeutics, diagnostics, and molecular sensors.  Based on the technology developed by Andrew D. Ellington, our tool of choice for the development of these applications is an "aptamer," an oligonucleotide binding species.  We use the methods of in vitro selection methodology to identify aptamers against a variety of targets.

 

Principal Investigator and Director (2016-present) of the University of Texas High School Research Initiative. The $1.3 million dollar NIH Science Education Partnership Award supported program is an inquiry training resource center, providing dual-enrollment research courses, teacher training, and inquiry resources. As the director, I am responsible for sustainability and fundraising efforts, communication with stakeholders, high school teacher and University research collaborator recruitment and training, program evaluation coordination, and dissemination of results. In 2019, the fourth year of the program, the HRI has had a sizable impact:  242 high school students, ~26 UT undergraduate peer mentors, 13 high school teachers, 8 high schools (including three Title I schools), 7 UT faculty research collaborators, and 5 school districts.

Faculty Council member representing tenure-track and non-tenure-track faculty, The University of Texas at Austin (August 2019 – August 2021) The Faculty Council is one of the two legislative bodies here at the University. It serves as the faculty’s voice and advises the administration on matters regarding undergraduate educational policy, including requirements for degrees, admissions, and honors, as well as recommendations from special and standing University committees. As a Faculty Council member, I serve on the University of Texas Press Advisory Committee, which, among other responsibilities, is responsible for considering and recommending proposed publications to bear the imprint of the Press. For more details regarding the Council, please consult its website at the following URL: https://facultycouncil.utexas.edu/.

Internal Advisory Committee Member, Texas Institute for Discovery Education in Science, The University of Texas at Austin (2016 – 2019), provide input on a variety of matters such as the compositions of committees (e.g. Review, Course and Curriculum, Promotion Committees), strategic planning, and use of funds.

Outreach Task Force Member, Non-Tenure Track Faculty College of Natural Sciences, The University of Texas at Austin (April 2019-present). This group strengthens the relationships within the CNS Outreach community, develops an interconnected outreach ecosystem, and helps NTTF faculty plug into service opportunities.

 

A part of the University of Texas Freshman Research Initiative, the Aptamer Stream uses oligonucleotide chemistry, in vitro selection methodology, and biochemistry to develop novel therapeutics, diagnostics, and molecular sensors.  Based on the technology developed by Andrew D. Ellington, our tool of choice for the development of these applications is an "aptamer," an oligonucleotide binding species.  We use the methods of in vitro selection methodology to identify aptamers against a variety of targets.

  1. Stovall GM, Huynh V, Engelman S, Ellington AD: Aptamers in Education: Undergraduates Make Aptamers and Acquire 21st Century Skills Along the Way. Sensors 2019, 19 (15) 3270. doi: 10.3390/s19153270.
  1. Clark G, Russell J, Enyeart P, Garcia, B, Wessel A, Jarmoskaite I, Polioudakis, D, Stuart Y, Gonzalez T, MacKrell A, Rodenbusch S, Stovall GM, Beckham J, Montgomery M, Tasneem T, Jones J, Simmons S, Roux S: Science Educational Outreach Programs That Benefit Students and Scientists.* PLoS Biology 2016, 14 (2):e1002368. doi: 10.1371/journal.pbio.1002368. *A 2016 top 50 most downloaded article (PLOS Biology, May 2017).
  1. Beckham JT, Simmons SL, Stovall GM, Farre J. “Chapter 10: The Freshman Research Initiative as a Model for Addressing Shortages and Disparities in STEM Engagement.” Directions for Mathematics Research Experience for Undergraduates. E-book. Ed. Mark A. Peterson, Ed. Yanir A Rubinstein. World Scientific, 2015. 181-212. doi: 10.1142/9789814630320_0010.
  1. Stovall GM, Bedenbaugh R, Singh S, Meyer AJ, Hatala PJ, Ellington AD, Hall B: In Vitro Selection Using Modified or Unnatural Nucleotides.  Current Protocols in Nucleic Acid Chemistry 2014, 9.6.1–9.6.33.  doi: 10.1002/0471142700.nc0906s56.
  1. Ledbetter MP, Hwang, TW, Stovall GM, Ellington AD: Continuous in vitro Evolution of a Ribozyme Ligase: A Model Experiment for The Evolution of a Biomolecule. Biochemistry and Molecular Biology Education 2013, 41(6):433-42.  doi: 10.1002/bmb.20742.
  1. Stovall GM: Evaluation of Protein Aggregation and Organismal Fitness.  PhD Dissertation, University of Texas at Austin, May 2011. 
  1. Narayanaswamy R, Levy M, Tsechansky M, Stovall GM, O’Connell J, Mirrielees J, Ellington AD, Marcotte EM: Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation.  Proceedings of the National Academy of Sciences USA 2009, 106(25):10147-52. doi:10.1073/pnas.0812771106.
  1. Li N, Ebright JN, Stovall GM, Chen X, Nguyen H, Signh A, Syrett A, Ellington AD: Technical and Biological Issues Relevant to Cell Typing by Aptamers.  Journal of Proteome Research 2009, 8(5):2438-48. doi:10.1021/pr801048z.
  1. Lee JF, Stovall GM, Ellington AD: Aptamer therapeutics advance. Current Opinion in Chemical Biology 2006, 10:282-289. doi:10.1016/j.cbpa.2006.03.015.
  1. Stovall GM, Cox JC, Ellington AD: Automated optimization of aptamer selection buffer conditions. Journal of the Association for Laboratory Automation 2004, 9:117-22. doi:10.1016/j.jala.2004.04.010.

The University of Texas College of Natural Sciences Teaching Excellance Award in Molecular Biosciences (2014).

Recognized by Services for Students with Disabilities for creating “an inclusion environment for all students at The University” (UT-Austin, 2016);